Cross-strand disulfides in the hydrogen bonding site of antiparallel β-sheet (aCSDhs): Forbidden disulfides that are highly strained, easily broken
نویسندگان
چکیده
منابع مشابه
Conformational analysis and design of cross-strand disulfides in antiparallel β-sheets.
Cross-strand disulfides bridge two cysteines in a registered pair of antiparallel β-strands. A nonredundant data set comprising 5025 polypeptides containing 2311 disulfides was used to study cross-strand disulfides. Seventy-six cross-strand disulfides were found of which 75 and 1 occurred at non-hydrogen-bonded (NHB) and hydrogen-bonded (HB) registered pairs, respectively. Conformational analys...
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Recently, transition metal dichalcogenides (TMDs), represented by MoS2, have been proven to be a fascinating new class of electrocatalysts in hydrogen evolution reaction (HER). The rich chemical activities, combined with several strategies to regulate its morphologies and electronic properties, make MoS2 very attractive for understanding the fundamentals of electrocatalysis. In this review, rec...
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A novel way of synthesizing unsymmetrical disulfides from thiols with DDQ is presented here. This procedure ran in a straightforward manner to give high product yields. Unsymmetrical disulfides were directly synthesized from the corresponding mixture of thiols in equimolar amounts under mild conditions. 2011 Elsevier Ltd. All rights reserved.
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The redox state of cellular thiols is widely studied because it was recently linked to many different diseases and pathologies. In this work we quantified the concentrations of protein disulfides (PSSP) and thiol-protein mixed disulfides (XSSP) in rat tissues (liver, kidney and heart) and cells (Raw 264.7) by an improved method of XSSP and PSSP determination after oxidative stress induced by di...
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Using electrodeposition of cyclic and acyclic Fc-peptide disulfides tightly-packed Fc-peptide monolayers were conveniently formed, which exhibit significant differences in their electron transfer kinetics.
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ژورنال
عنوان ژورنال: Protein Science
سال: 2018
ISSN: 0961-8368
DOI: 10.1002/pro.3545